MEPSGEN

PRODUCT

REPRESENTATIVE MODELS

MEPS-TBC-WL

MEPS-BBB model illustration

MEPS-BBBBlood-Brain Barrier

Provides perfusion flow to vascular endothelial cells
Supports tri-culture BBB cell configuration
Reconstructs 3D astrocyte culture with polarized end-feet formation
Assesses time- and dose-dependent human cell responses to compound exposure
Evaluates BBB permeability and transport mechanisms of test compounds
Evaluates the targeting efficacy for brain cells like glia

MEPS-SKN model illustration

MEPS-SKNEpidermis-Dermis Interface

Established a human skin cell co-culture model with keratinocytes and fibroblasts for skin tissue simulation
Study UVB-induced skin damage and aging-related responses, such as inflammation, and oxidative stress
Evaluate anti-wrinkle cosmetic candidates, by monitoring collagen degradation, MMP expression, and inflammatory-related biomarkers

MEPS-CEB model illustration

MEPS-CEBCorneal Epithelial Barrier

Provides perfusion flow to the corneal endothelium
Tri-cultured corneal cells: epithelium, stroma, and endothelium
Forms a functional corneal barrier under ALI conditions
Enables dynamic analysis of drug response (time/dosage)
Evaluates drug permeability across the corneal layers
Assesses ocular toxicity and barrier integrity (including TEER)

MEPS-BPB model illustration

MEPS-BPBBlood-Placenta Barrier

Co-cultured placental cells: trophoblasts and vascular endothelial cells
Mimics early placental development, including trophoblast invasion and vascular remodeling
Enables analysis under hypoxic and normoxic conditions to simulate early pregnancy
Assesses vascular barrier integrity and remodeling via TEER and junctional markers

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