MEPS-IMBIntestinal Mucosal Barrier
- Constructed using Caco-2 cells to replicate human intestinal epithelial characteristics
- Applies rhythmic fluid flow to mimic peristaltic motion and mechanical stimulation
PRODUCT
REPRESENTATIVE MODELS
MEPS-TBC-CH
MEPS-VEBVascular Endothelial Barrier
- Provides continuous perfusion flow to vascular endothelial cells
- Supports multiple human endothelial cell types, including iBMEC, hBMEC, and HUVEC, depending on vascular origin
- Reconstructs a tight and functional endothelial barrier under flow, mimicking in vivo vascular integrity
- Evaluate vascular permeability and leakage, using barrier integrity readouts such as tracer transport and TEER
MEPS-BRBBlood-Retina Barrier
- Provides perfusion flow to the retinal vascular endothelium
- Co-cultured retinal endothelial and epithelial cells
- Enables dynamic response analysis under various drug administration conditions (time/dosage)
- Evaluates drug permeability across the blood–retina barrier
- Assesses targeting efficacy for retina-relevant cells in ophthalmic drug development
MEPS-TEBTubular Epithelial Barrier
- Co-cultured tubular epithelial and endothelial cells
- Functionally recapitulates proximal tubule and distal nephron epithelia
- Evaluate nephrotoxicity and drug-induced kidney injury
- Enable reproducible kidney modeling under dynamic flow, with real-time monitoring of barrier formation and disruption
